AOD-9604

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Purity Guarantee

$60.00

AOD-9604 is a fragment of human growth hormone (HGH): specifically the section responsible for fat metabolism, isolated from the rest of the molecule. Unlike full HGH or GH secretagogues, AOD-9604 does not raise IGF-1 or affect blood sugar, making it safer for people with metabolic concerns. It stimulates lipolysis (fat breakdown) and inhibits fat accumulation, particularly in stubborn fat depots.

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Purity guarantee. If an independent assay of your lot returns below the purity stated on its certificate, we replace the order or refund it in full — no return shipment required.

Sold for laboratory research and further manufacturing use only. Not a drug, food, cosmetic, or dietary supplement. Not for human or veterinary use, and not for diagnostic or therapeutic purposes. Buyer is responsible for compliance with all applicable regulations.

Lyophilized Research Compound

Technical Overview

AOD-9604 is a synthetic peptide fragment corresponding to amino acid residues 176–191 of the human growth hormone sequence. This C-terminal fragment is studied in controlled laboratory settings for its role in receptor binding investigations and metabolic signaling research. Each batch is produced via solid-phase peptide synthesis (SPPS) and purified by reverse-phase HPLC, with third-party analytical documentation confirming purity and identity.

Purity: ≥99% by HPLC
Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S₂
Molecular Weight: 1815.08 g/mol
Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (disulfide Cys7-Cys15)
Synonyms: hGH fragment 176-191 analogue
Physical Form: Lyophilized powder
Solubility: Soluble in bacteriostatic water; consult the product COA for specific solvent recommendations.
Storage: Store lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; refrigerate reconstituted solution at 2-8°C.

Frequently Asked Questions

What is AOD-9604?

AOD-9604 is a synthetic peptide fragment corresponding to residues 176 to 191 of the human growth hormone sequence. It is also referred to as hGH fragment 176-191 analogue, and is supplied as a lyophilized powder as a reference compound for laboratory research only.

What is the structure of AOD-9604?

AOD-9604 is a 16-residue peptide with the sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe, closed by a disulfide bond between Cys7 and Cys15. The molecular formula is C78H123N23O23S2 with a molecular weight of 1815.08.

Why does AOD-9604 have a disulfide bond?

The Cys7-Cys15 disulfide bridge holds the fragment in the loop conformation it adopts within the full growth hormone molecule. Without it the sequence would be linear and would not reproduce the parent structure.

What is the difference between AOD-9604 and human growth hormone?

Human growth hormone is a 191-residue protein. AOD-9604 reproduces only the final 16 residues of that sequence, so it lacks the receptor-binding regions of the parent molecule. This fragment-versus-parent comparison is the basis of most AOD-9604 research.

What is AOD-9604 used for in research?

Common applications include receptor binding investigations, metabolic signaling studies, lipid metabolism models, and structure-activity work comparing the fragment against the full-length hormone.

Why is the 176-191 region studied specifically?

The C-terminal region of growth hormone was identified as the portion associated with metabolic activity in early fragment studies. Isolating it allows researchers to examine that activity separately from the growth-promoting regions elsewhere in the sequence.

What form is AOD-9604 supplied in?

AOD-9604 ships as a lyophilized powder in a sealed vial. Consult the certificate of analysis for the solvent recommendations that apply to your lot.

What purity is AOD-9604 supplied at?

Purity is 99% or greater as verified by HPLC. Lot-specific results are reported on the certificate of analysis accompanying each vial, and that figure is what our purity guarantee is measured against.

How should AOD-9604 be stored?

Store the lyophilized vial at -20 degrees Celsius, protected from light and moisture. Once reconstituted with bacteriostatic water, refrigerate the solution at 2-8 degrees Celsius and follow your laboratory's established protocols.

How is the vial shipped?

Orders leave the same business day when placed before 2pm EST, in an insulated mailer with a phase-change pack. Shipping is free on orders over $150.

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