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≥99% purity — HPLC + mass spec

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EPITHALON

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  • Purity Guarantee
$60.00

Epithalon is a synthetic tetrapeptide based on Epithalamin, a naturally occurring compound from the pineal gland. It was developed by Russian scientist Vladimir Khavinson, who has published extensively on its effects. Epithalon activates telomerase, the enzyme that lengthens telomeres (the protective caps on chromosomes that shorten with each cell division). Longer telomeres are associated with slower biological aging. Animal studies show extended lifespan. Human data is more limited but spans several decades of Russian clinical use.

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Purity guarantee. If an independent assay of your lot returns below the purity stated on its certificate, we replace the order or refund it in full — no return shipment required.

Sold for laboratory research and further manufacturing use only. Not a drug, food, cosmetic, or dietary supplement. Not for human or veterinary use, and not for diagnostic or therapeutic purposes. Buyer is responsible for compliance with all applicable regulations.

Lyophilized Research Compound

Technical Overview

Epitalon (EPI) is a synthetic tetrapeptide composed of the amino acid sequence Ala-Glu-Asp-Gly (AEDG), studied in laboratory environments for peptide signaling pathways and cellular regulatory mechanisms. This research peptide is synthesized by solid-phase peptide synthesis (SPPS) and purified by reverse-phase HPLC, with batch analytical documentation available for controlled biochemical experimentation.

Purity
≥99% by HPLC
CAS Number
307297-39-8
Molecular Formula
C14H22N4O9
Molecular Weight
390.35 g/mol
Amino Acid Count
4
Sequence
H-Ala-Glu-Asp-Gly-OH
Synonyms
Epitalon; AEDG
Physical Form
Lyophilized powder
Solubility
Soluble in water & bacteriostatic water
Storage
Store lyophilized at −20°C, protected from light & moisture

Frequently Asked Questions

What is Epithalon?

Epithalon is a synthetic tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly. It is also written as Epitalon or AEDG, and is supplied as a lyophilized powder as a reference compound for laboratory research only.

What is the structure of Epithalon?

Epithalon is a four-residue peptide, H-Ala-Glu-Asp-Gly-OH, with the molecular formula C14H22N4O9, a molecular weight of 390.35, and CAS number 307297-39-8. At four residues it is among the shortest peptides in the catalog.

What does AEDG stand for?

AEDG is the single-letter amino acid code for the sequence: alanine, glutamic acid, aspartic acid, glycine. Epithalon, Epitalon, and AEDG all refer to the same tetrapeptide.

What is Epithalon used for in research?

Common applications include telomerase expression studies, peptide signaling pathway investigation, cellular regulatory mechanism work, and pineal-related research models.

How does Epithalon relate to Epithalamin?

Epithalamin is a pineal gland peptide extract. Epithalon is the synthetic tetrapeptide developed from work on that extract, offering a single defined sequence in place of a mixture. The two are frequently compared in the source literature.

Why is telomerase a focus in Epithalon research?

Telomerase maintains telomere length, and reported effects on telomerase expression in cultured cells are the most-cited finding in the Epithalon literature. This makes it a recurring tool compound in cellular senescence work.

Why is such a short peptide of research interest?

Short peptides are simple to synthesize and characterize, which makes structure-activity relationships easier to isolate. A four-residue sequence leaves little ambiguity about which portion of the molecule drives an observed interaction.

What form is Epithalon supplied in?

Epithalon ships as a lyophilized powder in a sealed vial. It is soluble in bacteriostatic water; consult the certificate of analysis for the solvent recommendations that apply to your lot.

What purity is Epithalon supplied at?

Purity is 99% or greater as verified by HPLC. Lot-specific results are reported on the certificate of analysis accompanying each vial, and that figure is what our purity guarantee is measured against.

How should Epithalon be stored?

Store the lyophilized vial at -20 degrees Celsius, protected from light and moisture. Once reconstituted with bacteriostatic water, refrigerate the solution at 2-8 degrees Celsius and follow your laboratory's established protocols.

How is the vial shipped?

Orders leave the same business day when placed before 2pm EST, in an insulated mailer with a phase-change pack. Shipping is free on orders over $150.

Do I need a prescription to order?

Our peptides require a doctor referral. If you do not have one, use the Get a Prescription button to start a telehealth consultation, and your approved products will unlock on your account.

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